Bringing new chemistry to life

Life Reimagined


17:00 - 17:45

Not satisfied with nature’s vast enzyme repertoire, we want to create new ones and expand the space of genetically encoded enzyme functions. I will describe how we can use the most powerful biological design process, evolution, to optimize existing enzymes and invent new ones, thereby circumventing our profound ignorance of how sequence encodes function.

Mimicking nature’s evolutionary tricks and using a little chemical intuition, we can generate whole new enzyme families that catalyze important reactions, including ones not known in biology. These new chemical capabilities increase the scope of molecules and materials we can build using synthetic biology.

Frances Arnold2

Frances Arnold

Frances Arnold’s research focuses on protein engineering by directed evolution, wi...